Personalized Cancer Tests

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What is a Personalized Cancer Test?
- Detects early signs of those with developing cancer
- Helps to keep track of current schedule
- Provides the determination of personalized methods and natural treatment methods for the best treatment option
Circulating cancer cells are cancer cells that break off from the primary tumor and mix with blood cells or lymphatic organs. These organizations cause cancer progression and metastasis. There are many projects related to detecting these cells. DrHeal has developed a method with 86.6% sensitivity and 83.3% specification. It guarantees the precise and accurate detection and isolation of cancer development in this model, where it does not develop.

Chemosensitivity Test
Interest in personalized cancer treatment is increasing day by day. The chemosensitivity test is one of the methods of applying personalized cancer treatment and it provides the determination of the chemotherapy drugs or natural ingredients that will be most effective on the cancer cell of the patient. The chemosensitivity test is a blood test (tissue testing may be required in some cases). Tumor cells isolated from the samples are subjected to the following analyzes;
- The effectiveness of chemotherapy
- Genetic analysis for the effectiveness of targeted therapies
- Efficiency and availability of products with natural ingredients
The results are presented in a written report to the doctor who will administer the treatment. In addition, DrHeal provides information on how the patient can obtain specific chemotherapy drugs. While our genetic research determines the most effective treatment for the patient, it also detects important side effects that may develop during treatment.

Scientific Evidence
It has been reported in the literature that the response to empirical cancer treatment is between 5-7.5% (Royal North Shore Hospital ClinOncol (R Coll Radiol) 2005 Jun;17(4):294). The pharmaceutical industry evaluates diffuse chemosensitivity; however, cancer occurs as a result of genetic damage and each patient's genetic fingerprint is different from the other.

Therapeutic Concept
The tumor consists of subgroups of cells with different characteristics. These subgroups are associated with disease progression, treatment resistance, and relapse. When the patient is treated and current diagnostic methods do not detect any signs of disease, there are 10^9 to 10^12 cancer cells in the circulation. This is defined as remission. At this stage, only cancer stem cells can survive and colonize and cause metastasis. The purpose of our test is to determine which treatment the cancer cell will respond to, as well as to detect and treat these circulating cancer stem cells. Our main goal is to detect, analyze and screen cancer at every stage.

BLUE BOXES
Oncocount

It detects the presence and concentration of circulating tumor cells. Detects only precursor cells (CTCs) with potential for relapse and recurrence.
Test details:
- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample is required
- The final result is given in 7-10 days
- The test fee differs according to the tax rates in the country


Oncotrace
Detects the presence of CTCs. Provides information on CTCs immunophenotyping.
Test details:
- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample is required
- The final result is given within 7 days
- The test fee differs according to the tax rates in the country


Oncotrail
It provides information on the presence and concentration of CTCs and immunophenotyping of specific cancer types. This test is used to monitor specific blood types (such as breast, prostate, sarcoma, etc.).
Test details:
- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample is required
- The final result is given in 7-10 days
- The test fee differs according to the tax rates in the country

Onconomics
It is used to evaluate the effectiveness of drugs specific to cancer cells obtained from the patient.
Test details:
- The test can be applied to all cancer types
- 15-25 ml of peripheral blood sample or a minimum of 400 mg of tissue sample is required.
- The final result is given in about 7-10 days
- The test fee differs according to the tax rates in the country


Oncomics Plus
It is used to evaluate the effectiveness of drugs specific to cancer cells obtained from the patient. Three methods are used for evaluation; direct cytotoxic effect, immune system stimulation and inhibition of proliferative signal in cancer cells.
Test details:
- The test can be applied to all cancer types
- 15-25 ml of peripheral blood sample or a minimum of 400 mg of tissue sample is required.
- The final result is given in about 7-10 days
- The test fee differs according to the tax rates in the country

Onconomics Extracts
It gives information about the effectiveness of natural biological substances that are effective on cancer cells. Three methods are used for evaluation; direct cytotoxic effect, immune system stimulation and inhibition of proliferative signal in cancer cells.
Test details:
- The test can be applied to all cancer types
- 15-25 ml of peripheral blood sample or a minimum of 400 mg of tissue sample is required.
- The final result is given in about 7-10 days
- The test fee differs according to the tax rates in the country

ChemoSNIP
SNP Analysis of cytotoxic drugs
Pharmacogenomics is the science that examines how the patient will respond to a drug (good response, bad response or no response) by examining gene variations.
Single Nucleotide Polymorphisms (SNPs) are how people get sick; DNA sequence variations that determine how it responds to chemicals, drugs, or other agents.
ChemoSNIP works on SNPs that are involved in the metabolism and detoxification of cytotoxic or targeted therapies used in cancer treatment.
Test details:
- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample or 2 buccal mucosal samples are required
- The final result is given in about 10-12 days
- The test fee differs according to the tax rates in the country

Metastat Test
It is the CTCs Marker that marks the organ that is potent for relapse. Many markers have been associated with specific organ metastases in the literature. The metastat test allows the collection of specific markers obtained in specific organs. The cells of the primary tumor express genes and proteins specific to the organ to which they will metastasize, with genetic information.
Test details:
- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample is required
- The final result is given in about 7-10 days
- The test fee differs according to the tax rates in the country

Immune – Frame Test
This test is focused on the immune system and immunity.
Test details:
- The test is suitable for all types of cancer
- 15-25 ml of peripheral blood sample is required
- The final result is given in about 7-10 days
- The test fee differs according to the tax rates in the country
aCGH Test
Imbalanced chromosomal abnormalities cause various genetic diseases such as cancer. aCGH can be used to detect imbalances in the whole genome. This may be useful in detecting the primary source of the tumor.
Test details:

- The test can be applied to all cancer types
- 7-10 ml of peripheral blood sample is required
- The final result is given in about 3-4 weeks
- The test fee differs according to the tax rates in the country


SUGGESTIONS FOR TEST CHOICES:
Tests recommended for the detection of drugs to be used against the disease:
- Onconomics
- Onconomics Plus

Tests recommended in patient follow-up:
- Oncocount
- Oncotrace
- Oncotrail

What is the recommended timeframe for follow-up?
Every three months in the first year, then every six months

Which test focuses on the immune system?
- Immune – Frame

Which test will show which drug will be effective in a patient's cancer?
- ChemoSNiP

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